Dry mouth causes: medications, aging and what helps after 65

Dry mouth causes explained: medications, diabetes, Sjögren's and more. Learn the signs, what helps and how to protect your teeth and dentures after 65.
Older man pouring himself a glass of water in the kitchen

Dry mouth (xerostomia) happens when your mouth does not make enough saliva. In older adults, the most frequent cause is usually medication: drugs for blood pressure, depression, bladder control or allergies, among hundreds of others. Diabetes, Sjögren's disease, radiation treatment and mouth breathing can also cause it, and it is not a normal part of getting older.

If you wake up with your tongue stuck to the roof of your mouth, or bread is suddenly hard to swallow, you are not alone. There is a reason for it, and there is a lot you can do to feel better and protect your teeth.

What is dry mouth, and why does saliva matter so much?

Everyone gets a dry mouth now and then, for example when nervous. It becomes a problem when it happens all or most of the time, according to the National Institute of Dental and Craniofacial Research (NIDCR). Then chewing, swallowing and even talking can get harder.

Saliva does more work than most people realize. MedlinePlus explains that it:

  • washes food bits off your teeth and gums;
  • carries calcium and phosphate, which help protect teeth from cavities;
  • contains antibodies that help fight mouth and throat infections.

With too little saliva, the risk of cavities and fungal (yeast) infections goes up (NIDCR).

Cavities on the root of the tooth

With age, many people have some gum recession, which leaves the root of the tooth exposed. The MedlinePlus medical encyclopedia notes that this is why cavities in older adults are more likely to form on the root. A dry mouth also lets bacteria build up more easily. If you notice your gums pulling back, read receding gums and loose teeth.

Dry mouth causes: the most common ones

Medications

In older adults, medication is probably the most common cause (MedlinePlus). The NIDCR's Dry Mouth: Questions and Answers guide says more than 400 medicines can make the salivary glands produce less saliva. These are the ones the NIDCR and the MedlinePlus encyclopedia mention most, prescription and over-the-counter alike:

  • high blood pressure medicines;
  • antidepressants and anti-anxiety medicines;
  • bladder control medicines;
  • antihistamines (for allergies) and decongestants;
  • some medicines for pain, heart disease, asthma or epilepsy.

Important: never stop or change a medication on your own. Talk to your doctor or pharmacist about alternatives. Sometimes there are options, but that decision belongs to your doctor.

Health conditions

  • Diabetes. The NIDCR lists it among the diseases that can dry out the mouth. If your mouth is often dry, mention it to your doctor too.
  • Sjögren's disease. The immune system attacks the glands that make tears and saliva. Most people are diagnosed after 50, and women are nine times more likely than men to have it (NIDCR). If you have dry eyes and a dry mouth, tell your doctor.
  • Others: HIV, Parkinson's disease, Alzheimer's disease or a stroke (MedlinePlus).

Radiation and cancer treatment

Radiation to the head and neck can damage the salivary glands, and chemotherapy can make saliva thicker (NIDCR). If you are about to start radiation, ask for a dental checkup first.

Mouth breathing, tobacco and alcohol

Sleeping with your mouth open, smoking and drinking alcohol all dry the mouth. MedlinePlus also lists dehydration and stress.

Age and taking several medicines

Aging by itself does not cause dry mouth. But older adults tend to have more health conditions and take more medicines, and that raises the risk (MedlinePlus). Taking several drugs that dry the mouth adds up.

Signs of dry mouth

The NIDCR describes these signs:

  • a sticky, dry feeling in the mouth;
  • trouble chewing, swallowing, tasting or speaking;
  • burning or itching in the mouth or throat;
  • cracked lips and a dry, rough or cracked tongue;
  • mouth sores or infections that keep coming back;
  • bad breath (if that sounds familiar, read bad breath: causes and what to do).

What helps dry mouth day to day

These steps bring relief. They do not fix the cause, but they make the day easier:

  1. Sip water through the day, and drink water or sugarless drinks with meals. The NIDCR suggests 8 to 12 cups a day; if your doctor has limited your fluids, follow their advice.
  2. Chew sugarless gum or suck on sugarless hard candy. Both stimulate saliva. Some contain xylitol, which may help prevent cavities (NIDCR).
  3. Skip alcohol-based mouthwashes. They can dry you out more. Use rinses made for dry mouth instead (MedlinePlus).
  4. Limit caffeine (coffee, tea and some sodas), alcohol and tobacco.
  5. Go easy on spicy and salty foods and acidic juices, which sting in a dry mouth.
  6. Try a saliva substitute (artificial saliva gel or spray) from the pharmacy. Ask which one suits you.

Keep your expectations realistic. A Cochrane review of 36 trials found no strong evidence that any product applied in the mouth reliably relieves dryness. Gum does increase saliva in people who still make some.

If your glands still make some saliva, your doctor or dentist may prescribe a medicine that helps them work better (NIDCR).

Dry mouth at night

Many people notice it most when they wake up. What helps:

  • run a humidifier in the bedroom while you sleep;
  • try to breathe through your nose (MedlinePlus);
  • if you snore or sleep with your mouth open, tell your doctor.

Protecting your teeth: extra fluoride and dentures

With a dry mouth, daily care matters even more. The NIDCR recommends brushing gently at least twice a day with fluoride toothpaste, flossing and avoiding sticky, sugary foods. If you do eat them, brush soon after.

Extra fluoride your dentist may recommend

If your dry mouth comes from medication, your cavity risk is higher. At the office, your dentist or hygienist may apply a fluoride varnish or foam (NIDCR, Older Adults and Oral Health). For home, they may suggest a prescription fluoride gel or a fluoride rinse. More in fluoride in Florida's water.

If you wear dentures

A dry mouth can make dentures feel uncomfortable and fit less well. Without saliva, they can rub your gums or the roof of your mouth and cause sore spots. Yeast infections can also develop under the denture (NIDCR).

  • Wet your mouth with water before putting your denture in and during meals.
  • Ask whether a saliva substitute could help.
  • If it rubs or moves, do not wait: read loose dentures: what to do.
  • Even with no natural teeth, keep seeing a dentist. Thinking about a new denture? See dentures in Miami.

When to book a visit

Schedule a checkup if:

  • your mouth is dry most days and it is not getting better;
  • you keep getting new cavities, especially near the gumline;
  • you have sores, burning or white patches in your mouth (MedlinePlus);
  • your denture rubs or no longer fits;
  • you started a new medicine and your mouth feels drier. Let your doctor know too.

When not to wait: if your face or jaw is swollen, or you have a fever, call your dentist the same day. If you have trouble breathing or swallowing, call 911 or go to the emergency room.

Tip from the PureSmile team

Before your visit, write down every medicine you take, including over-the-counter pills, vitamins and allergy drops. Or bring the bottles in a bag. That way the dentist can spot what might be drying your mouth and tell you what to bring up with your doctor.

How we do it at PureSmile

PureSmile Miami opens on November 2, 2026, at 8000 SW 117th Ave, Suite 100, in Kendall. At your first visit, our dentist examines your mouth, goes over your medication list and walks you through your X-rays to show whether any early cavities are starting and what extra protection makes sense for you. We see patients in English or Spanish, verify your insurance for free and give you a written treatment plan before we start.

Join the waitlist or call us at (305) 787-3642.

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Frequently asked questions

What medications cause dry mouth?

Hundreds do, including drugs for high blood pressure, depression, bladder control and allergies. Do not stop any of them on your own: talk to your doctor or pharmacist.

Why is my mouth so dry at night?

Often it is from sleeping with your mouth open, dry air or medicines you take. A bedroom humidifier and breathing through your nose can help.

What should I drink for dry mouth?

Water, sipped through the day and with meals, or sugarless drinks. It helps to limit coffee, alcohol and acidic juices, which dry or sting.

Is dry mouth normal in older adults?

It is common, but it is not normal: aging alone does not cause it. There is usually a reason, such as medication, and it is worth finding with your dentist and your doctor.

Can dry mouth be a sign of diabetes?

Diabetes is one of the conditions that can cause dry mouth, according to the NIDCR. If your mouth is often dry and you do not know why, tell your doctor.

General information; not a substitute for an in-person evaluation. Sources: NIDCR (Dry Mouth; Dry Mouth: Questions and Answers; Sjögren's Disease; Older Adults and Oral Health); MedlinePlus (Dry Mouth; Medical Encyclopedia); Cochrane (topical therapies for dry mouth, 2021); MouthHealthy (ADA). Yoan Suárez Zayas, DMD · FL Lic. DN 21413.

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October 13, 2026